Genetics


‘Orphan Drugs’ Orphaned by Budget Cuts

By Ethan Porter

Advocates for sufferers of rare diseases are working to ensure passage of newly introduced legislation that would counteract a recent administrative action they say deprives those with such maladies of vital medicines.The Medicare Patient Access to Drugs for Rare Diseases Act of 2003, introduced in the House of Representatives July 10, is intendedRead More


Annual Guide to Jewish Genetic Diseases

The Forward presents this section to provide information on some of the more serious Jewish genetic diseases. There are about 20 “Ashkenazic diseases,” not counting the higher rates of at least four cancer-related genes. The diseases are more prevalent in the Eastern European Jewish population because of centuries of endogamy, literally,Read More


LOTS Sufferers Combat Ignorance as Well as Symptoms

By Rachel Zuckerman

When people find out Shirley Webb has late onset Tay-Sachs disease (LOTS), their reactions have ranged from “But you’re older than 5 years old!” to “Why are you alive?” Once, at work, someone saw her pull away from her desk in her wheelchair and exclaimed, “I didn’t know you were crippled!”At 66, Webb, a co-founder of theRead More


Drug Trial Brings Hope to Late Onset Tay-Sachs Patients

By Rachel Zuckerman

Doctors are experimenting with an oral medication known as Zavesca as a possible treatment for late onset Tay-Sachs (LOTS) disease, it was reported at a conference in Philadelphia last month.New York University School of Medicine and Cleveland University Hospital both launched trials using the drug, whose chemical name is OGT918 or miglustat, onRead More


How a Mother Overcame a Malady

By Andrea Schleider

Kathryn Goldstein* of Monroe, N.Y., has no medical background, but this proud Orthodox mother of 11 has become an expert on one Jewish genetic disease. Three of her children were diagnosed with the genetic disorder, congenital hyperinsulinism.In 1978, after a healthy full-term pregnancy, Kathryn gave birth to Amanda, her seventh child. Two hoursRead More


Usher Gene Discovered

By Lea Winerman

Scientists have pinpointed the gene mutation responsible for most cases of Usher syndrome type 1 in Ashkenazi Jews. The syndrome is a genetic disorder that causes deafness from birth and progressive blindness beginning before age 10.The discovery, first reported in The New England Journal of Medicine in April, will allow doctors to more easily andRead More


Treatment Seen for Familial Dysautonomia

By Jonathan Friedman

Two New York doctors have discovered a treatment that is raising hope for sufferers of one of the Jewish genetic diseases.Sylvia Anderson and Berish Rubin, both of the Laboratory for Familial Dysautonomia Research at Fordham University, announced in May that a variant of vitamin E, tocotrienols, is effective as a treatment for familialRead More


Stem Cell Exports to Germany Causing Controversy in Israel

Two Israeli institutions, Haifa’s Technion Israel Institute of Technology and Rambam Medical Center in Haifa, began exporting stem cells culled from human embryos to Germany this year, arousing a storm of controversy within both countries’ scientific and medical communities.Because stem cells have enormous medical potential, many scientists,Read More


Doctor Writes ‘Epic Saga’ Of Jews in Medicine

By Max Gross

As Frank Heynick was nearing the completion of his gigantic tome, “Jews and Medicine: An Epic Saga,” he came across the name of an important doctor, George Sternberg, whom he had neglected to mention.The discovery of Sternberg did not make Heynick happy.“I got through a lot of trimming to keep it at 600 pages,” Heynick said. The ideaRead More


Colon Cancer Seen Linked to Bloom Gene

By Ross Schneiderman

Ashkenazi Jews are two to three times more likely to develop colon cancer if they carry the gene for Bloom syndrome, according to a September 2002 study by American and Israeli researchers.Dr. Kenneth Offit, senior author of the study and chief of the clinical genetics service at Memorial Sloan-Kettering Cancer Center in New York, saidRead More





Find us on Facebook!
  • Not a gazillionaire? Take the "poor door."
  • "We will do what we must to protect our people. We have that right. We are not less deserving of life and quiet than anyone else. No more apologies."
  • "Woody Allen should have quit while he was ahead." Ezra Glinter's review of "Magic in the Moonlight": http://jd.fo/f4Q1Q
  • Jon Stewart responds to his critics: “Look, obviously there are many strong opinions on this. But just merely mentioning Israel or questioning in any way the effectiveness or humanity of Israel’s policies is not the same thing as being pro-Hamas.”
  • "My bat mitzvah party took place in our living room. There were only a few Jewish kids there, and only one from my Sunday school class. She sat in the corner, wearing the right clothes, asking her mom when they could go." The latest in our Promised Lands series — what state should we visit next?
  • Former Israeli National Security Advisor Yaakov Amidror: “A cease-fire will mean that anytime Hamas wants to fight it can. Occupation of Gaza will bring longer-term quiet, but the price will be very high.” What do you think?
  • Should couples sign a pre-pregnancy contract, outlining how caring for the infant will be equally divided between the two parties involved? Just think of it as a ketubah for expectant parents:
  • Many #Israelis can't make it to bomb shelters in time. One of them is Amos Oz.
  • According to Israeli professor Mordechai Kedar, “the only thing that can deter terrorists, like those who kidnapped the children and killed them, is the knowledge that their sister or their mother will be raped."
  • Why does ultra-Orthodox group Agudath Israel of America receive its largest donation from the majority owners of Walmart? Find out here: http://jd.fo/q4XfI
  • Woody Allen on the situation in #Gaza: It's “a terrible, tragic thing. Innocent lives are lost left and right, and it’s a horrible situation that eventually has to right itself.”
  • "Mark your calendars: It was on Sunday, July 20, that the momentum turned against Israel." J.J. Goldberg's latest analysis on Israel's ground operation in Gaza:
  • What do you think?
  • "To everyone who is reading this article and saying, “Yes, but… Hamas,” I would ask you to just stop with the “buts.” Take a single moment and allow yourself to feel this tremendous loss. Lay down your arms and grieve for the children of Gaza."
  • Professor Dan Markel, 41 years old, was found shot and killed in his Tallahassee home on Friday. Jay Michaelson can't explain the death, just grieve for it.
  • from-cache

Would you like to receive updates about new stories?




















We will not share your e-mail address or other personal information.

Already subscribed? Manage your subscription.